Journal of Clinical Pediatrics 2009;(11):1093-1094,1100
doi:10.3969/j.issn.1000-3606.2009.11.025
Clinical application of atomoxetine in children with attention deficit hyperactivity disorder
Su YUAN ; Xu TONG
Keywords
atomoxetine; attention deficit hyperactivity disorder; children; treatment
Country
China
Language
Chinese
Abstract
Atomoxetine as a nonstimulant medicine was approved by the Chinese Food an Drug Administration and provide a new selection of treatment drugs for attention deficit hyperactivity disorder (ADHD). Tomoxetine is a noradrenaline transmitter reuptake inhibitor which can selectively inhibit synapsis noradrenaline transport protein, strengthen noradrenaline's resupination effect, and increase noradrenaline's activity released by synaptic cleft to improve the symptoms of the ADHD patients. Compared with methylphenidate, atomoxetine does not affect the concentration of the neurotransmitter dopamine and does not induce or increase the Tourettes' syndrome, therefore atomoxetine is more suitable to treat ADHD together with Tourettes syndrome. In this article the treatment of atomoxetine for ADHD, including the indications, dosage as well as adverse reactions and efficacy assessment are reviewed.
备案号: 11010502037788, 京ICP备10218182号-8)