Clinical observation was carried out in 12 patients with chronic heart failure refractory to digitalis, diuretics and vasodilators. Polysaccharide sulfact tablets were given for 15 days. Results showed that improvement of heart function was found in 8 cases, among which 5 cases were excellent and 3 cases fine. The overall clinical effective rate was 66. 7%. The drug had the faveorable effects to decrease blood viscosity, imporve microcirculation. etc. We consider that PSS may be used as a suplementary drug to treat CHF.