[Objective]To summarize febrile disease syndrome and treatment characteristics in“Common Treatise of Febrile Diseases”of Yu Genchu, add new meanings to the research of the doctrine of febrile disease. [Methods] Through col ating febrile disease contents in“Common Treatise of Febrile Diseases”to analyse and discuss. [Results] The name of febrile disease appears rarely in“Common Treatise of Febrile Diseases”,but the contents of the book contain febrile disease,such as febrile disease diagnosis,treatment and aftercare. [Conclusion]The name of “typhoid fever”is throughout the whole book,but as a scholar of younger age,we should know it is generalized “typhoid fever”, which is the name of seasonal exogenous disease.The book explains the original idea of Zhongjing and integrates with the theories of the doctors of febrile diseases, reflecting Yu Genchu ’s academic idea of cold-warm combination and initiating the research of Shao Pai Shang Han.