Journal of Clinical Pediatrics 2010;(1):10-12,17

doi:10.3969/j.issn.1000-3606.2010.01.003

Dysregulation of homeostasis and therapeutic option in septic shock

Chunfeng LIU

Keywords

septic shock; dysregulaton of endocrinologic; therapeutic option

Country

China

Language

Chinese

Abstract

Septic shock may have a lasting effect on all human endocrinologic, coagulatory and metabolic regulatory circuits with the consequence of severe dysregulation of homoeostasis.Adjunctive therapeutic options like correction of metabolic acidosis, intensive insulin therapy, and modulation of coagulation by drotrecogin alfa (activated) are still controversial.However, these adjunctive therapeutic options should be selected according to the national and international guidelines.