Chinese Traditional Patent Medicine 1992;0(02):-

Study on Antineoplastic Components of Zebrina Pendula Schnizl

Xiaoqi FAN ; Xingjie LIU

Keywords

antineoplastic components; Zebrina pendula Schnizl; ?-sitosterol; 3?; 5?; 6?-trihydroxy stigmast; succinic acid; anticancer test of ascites type-180 sarcoma of mice

Country

China

Language

Chinese

Abstract

Three components have been isolated from Zebrina pendula Schnizl and identified as ?-sitosterol, 3?, 5?, 6?-trihydroxy stigmast and succinic acid. As a result the anti-tumor rate were 43% (160mg/kg)for succinicacid, 91% (100mg/kg) for ?-sitosterol and 98%(100mg/kg) for 3?, 5?, 6?-trihydroxystigmast, respectively, after anti-cancer test of ascites type-180 sarcoma of mice. It was found that the last hadn't toxicity when its dose was increased.