Chinese Journal of Clinical Pharmacology and Therapeutics 2004;0(11):-

Protective effect of Cistanchis glycosides on ethanol-induced liver damage in mice

Huiying LUO ; Yuan LIU ; Guozhu XI ; Jiande DU

Keywords

Cistanchis glycosides; ethanol-induced liver damage; liver function; lipid overoxidation reactions

Country

China

Language

Chinese

Abstract

AIM:To research the protection of Cistanchis glycosides on ethanol-induced liver damage in mice.METHODS:40 mice were divided into 4 groups in random,and administered by gavage for 4 weeks.Cistanchis glycosides were twice a day,ethanol were once a day.When time limit arrived,mice were weighted,the serum was afforded to detect the liver function index,liver homogenate were prepared for biochemical detections,liver remained were fixed for pathological investigation.RESULTS:When mice were damaged by ethanol,liver index,liver function index,contents of TG,TC,MDA and LPO were increased distinctly(P