Chinese Pharmacological Bulletin 2003;0(10):-

The expression of TRAIL in psoriatic patients and healthy subjects

Jishun YANG ; Jianhua WU ; Quangang ZHU ; Jiyong LIU ; Jinhong HU

Keywords

TNF-related apoptosis-inducing ligand; psoriasis; skin; skin lesions; inflammation; apoptosis

Country

China

Language

Chinese

Abstract

Aim To explore the expression of TNF-related apoptosis-inducing ligand(TRAIL)between psoriatic patients and healthy subjects.Methods Immunohistochemical staining and Real-Time PCR methods were established to detect the expression of TRAIL.Results Immunohistochemical staining results indicated a significant difference of the expression of TRAIL between psoriatic patients and healthy subjects.Real-Time PCR results indicated that the quantities were 0.42?0.07,1.01?0.16 respectively of two type skins.Thus there were significant differences(P