Senile dementia is a common degenerative disease of center nervous system in old age.The pathogeny and pathomechanism haven't been made clear.And the precise therapy is lack.It is thought that the Heart and Spleen has physiological and pathological relevance with brain by analyzing the relation between the Heart and Spleen and senile dementia in the article.Using method of benefiting the Heart and Spleen in treating senile dementia not only improves the somatic symptoms,also delays the degeneration of intelligence of the patients.The point puts forward the new thinking and method to cure senile dementia.