Objective To evaluate the serum Level of B-natriure peptide(BNP)in elderly patients with Left Ventricular dysfunction and to determine the correlation between the BNPand hemodynamic Variable.Methods According to New York Heart Association(NYHA)class.51 patients with Left Ventricular dysfunction and 28 without Left Ventricular dysfunction(control group)were measured.BNP Levels were obtained,Left ventricular ejection fraction(LVEF)was assessed by echocardiography,center vein pressure(CVP)was determined in NYHA Class Ⅲ-Ⅳ groups.Results BNP were (39.32?5.51)ng/L in control group,respectively(265.94?63.13)ng/L in NYHA ClassⅡgroup(n=18),(569.93?109.17)ng/L 、CVP was(9.67?1.23)cmH_2O in NYHA class Ⅲ group,(2 764.33?1 020.53)、CVP was(19.61?4.57)cmH_2O in NYHA class Ⅳ.The difference of BNP and CVP in groups were scegnificant(all P