Objective To investigate the HOMA-IR and HOMA-? index in the diagnosis and judge the patients with vesting traumatic hemorrhagic MODS in the clinical and prognostic value,as well as the role of insulin resistance and decreased insulin secretion in energy metabolism disorder of patients with MODS.Early prevention and treatment of clinical provided for MODS.Methods 60 patients with traumatic MODS and 30 healthy adults participated in the study,were measured and compared their fasting blood glucose,insulin,lactate and pyruvicacad,glucagon and cortisol levels,calculated HOMA-IR,HOMA-?,and the lung,liver,kidney,pancreatic ? cells,and other major organ function in MODS patients parameters and indicators of the level of cells,HOMA-IR index were relevant and regression analysis.Results MODS group HOMA-IR index,fasting plasma glucagon and cortisol were significantly higher than the normal control group(P