88 patients with advanced schistosomiasis japonica complicated with hepatitis B, which was confirmed by positive HBsAg and/or HBcAg in liver with double perioxidase-anti-perioxidase (PAP) method, were analyzed clinically and pathologically. It was found that there were four pathological types in the livers of these patientss simple schistosomial liver fibrosis (SSLF, 16.3%), SSLF complicated with chronic hepatitis (18.2%), SSLF complicated with inactive cirrhosis (29.6%) and SSLF complicated with active cirrhosis(38.6%). Among the 88 patients, 43(48.9%) cases had no clinical manifestation associated with the damage of liver function and only 23(26.1%) cases had the history of acute hepatitis. The relationship between clinical manifestations and liver pathological changes was also discussed.