Ophthalmology in China 1994;0(02):-

Ascorbic acid inhibits the activity of collagenase

Yi WANG

Keywords

Ascorbic acid; Clostridiopeptidase A

Country

China

Language

Chinese

Abstract

Ascorbic acid was found to inhibit the activity of collagenase in vitro significantly at the concentration of 56.7mmlo/L and completely at the concentration of 85.0mmol/L. This effect was destroyed by heat. The experiment explained further the useful action of topical ascorbic acid in the treatment of corneal alkaline burn and ulcer.