Chinese Traditional and Herbal Drugs 1994;0(06):-

Antiinflammatory Effects of Alcohol Extract of Daoguaniou (Caesalpinia sepiaria var. pubescens)

Le LI ; Feier ZHUANG ; Zengli LI

Country

China

Language

Chinese

Abstract

An tiinflammatory effects of alcohol extract of Caesalpinia sepiarla Roxb. var. pubescent Tang et wang were shown by ip iujection. The extract significantly decreased xylene induced swelling of mice ear; carrageenin produced edema of hind paw in rats, and decreased volume of pleural exudate on carrageenin-induced acute pleurisy of rats. It also inhibited egg white induced arthritis iu rats.LD50 value is 303.7mg/kg by ip in mice, confidence limit of 95% is 296.5 ? 189.4mg/kg.