OBJECTIVE To prevent and control infection in hospital and enhance the disposable medical article management. METHODS Special training methods were enhanced for the staff in blood purified center of our hospital to improve their ability.And relative rules and regulations were enacted to enhance the management of the disposable medical articles. RESULTS The disposable medical articles management was standardized and systematized.From Jan 2004 to Dec 2005,all the used disposable medical articles were collected by the center of blood purification in Anzhen Hospital.Effectively prevented them from dispersing to the outside and reduce the incidence of infection.The rate up to standard in the examination about the hospital infections knowledge was 100%,and the rate of correct operation was 98%. CONCLUSIONS The key points to guarantee the medical system safety and the healthy condition of the patients and medical staff include reconstruction in minds,clear responsibility,effective management and reasonable use of the disposable medical articles.