Chinese Journal of Immunology 2000;0(09):-

The relationship of TNF-? and insulin resistance in patients with Gestational diabetes mellitus

Sheng YANG

Keywords

Gestational diabetes mellitus(GDM); TNF-?; Insulin resistance

Country

China

Language

Chinese

Abstract

Objective:To investigate the relationship between TNF-? and insulin resistance in GDM.Methods:To observe the changes of TNF-?, FBS, FINS and reproductive hormones during early and late gestation in normal group and GDM group.Results:The levels of TNF-?、HOMA-IR in late gestation of both groups are markedly higher than that in early gestation (P0.05).Conclusion:TNF-? is a major factor to effect the insulin resistance.