Journal of Practical Stomatology 1995;0(04):-

Experimental study of deep-frozen on the decrease of antigenicity of allogenic bone.

Xinghua FENG

Keywords

Freezing; Bone implantation; Cellular immunity

Country

China

Language

Chinese

Abstract

Cellular immunological reaction of the subjects after transplantation of deep-frozen (at -196℃) al-logenic bone grafts was studied using the sensitive LDH - release assay of morden immunological technique. The antigenicity of allogenic bone was definitely decreased after deep-freezing treatment and related to the time of treatment. In the experimental models the antigenicity of the deep-frozen allogenic bone was reduced to the same level as that of isogenic bone when it had been frozen at-196℃ for 7 days.