Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(07):-

Significance of Fas, FasL and FADD expression in squamous cell carcinoma of larynx

Haili SUN ; Hua GUO ; Yuhe LIU ; Ting LI ; Shuifang XIAO

Keywords

Laryngeal Neoplasms; Carcinoma, Squamous; Apoptosis Regulatory Proteins; Apoptosis

Country

China

Language

Chinese

Abstract

OBJECTIVE To investigate the expression and significance of Fas, FasL and FADD in laryngeal carcinoma. METHODS Immunohistochemical method was used to examine the expression of Fas, FasL and FADD in laryngeal carcinoma specimen and adjacent normal tissues. RESULTS The positive rates of Fas and FADD in laryngeal carcinoma tissue were significantly lower than that in adjacent normal tissue, while FasL in laryngeal carcinoma tissue was higher than that in adjacent normal tissue(P