OBJECTIVE To explore the application of n-butyl-cyanoacrylate to treat laryngopharyngeal sponge angioma.METHODS The therapy and outcome of 19 cases of laryngopharyngeal cavernous hemangiomas during 1994.1～2005.1 were analyzed retrospectively.The age of all the patients ranged from 18 to 67 years with an average of 40.2 years.15 of the 19 cases were sclerotherapied by injection of a new type of tissue adhesive NBCA.4 of the 19 cases were undergone dissection of the lesion by surgical approach combined with local injection of NBCA.The duration of Follow-up ranged from 1 to 7 years.RESULTS Complete remove of tumor was achieved in 16 cases(84.2%);the tumor of 3 cases(15.7%) was removed incompletely,whose residual tumor was ablated by YAG laser in outpatient. CONCLUSION The cavernous hemangioma occures rarely in laryngopharyngx and usually are poorly defined. It is difficult for treatment because of dangerous bleeding and airway obstruction.In this study,CT、MR and DSA were used to define the extent of disease,and a high cure rate were achieved by NBCA injection combined with surgery and laser ablation.