Objective To analyze the relationship between serum lipids level and different stroke subtypes. Methods 120 cases with stroke were divided into two groups randomly: cerebral infarction stroke(60)and hemorrhage stroke (60). 50 non-stroke cases were chosen as control group. Four indexes for blood lipids were determined in all patients. Results Levels of TG, TC, LDL-C in patients with cerebral infarction were significantly higher than those in the control group. There was no significant difference in serum lipid levels between the patients with cerebral hemorrhage and the controls. Conclusions It suggests that disturbance of serum lipid metabolism is a risk factor for cerebral infarction stroke, but no significant relationship was found between cerebral hemorrhage stroke and blood lipids disorder.