Chinese Journal of Forensic Medicine 1986;0(01):-

Study on blood drug level of 8 Lidocaine anaphylactic deaths

Yingqiang LU ; Zhaoyan XUAN ; Baijun CUI

Keywords

Forensic toxicology; Lidocaine; Anaphylactic shock; Blood drug level; High performance liquid chromatography(HPLC)

Country

China

Language

Chinese

Abstract

Objective To study the relationship between Lidocaine blood drug level and the cause of death from Lidocaine anaphylactic shock. Method Comparing and analyzing the blood drug levels by HPLC between two groups of people whose various indexes are normal before the surgery. Group 1 included 8 cases who accepted Lidocaine as anesthetic and died from Lidocaine anaphylactic shock. Group 2 included 11 cases who also took Lidocaine as anesthetic and passed the surgery smoothly. Results Lidocaine blood level of Group 1 (1.61?0. 45mg/L) is lower than that of Group 2 (2. 44 ?0. 47mg/L). Conclusion Lidocaine blood drug level has nothing to do with the cause of Lidocaine anaphylactic shock.