Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(01):-

The Study on Apolipoprotein E Gene Polymorphism Characteristics of Cerebral Infarction and Intracerebral Hemorrhage

Jinghua WANG ; Xianjia NING ; Hongyan LU

Keywords

Cerebrovascular Disease; Polymorphism; apo-E Gene

Country

China

Language

Chinese

Abstract

Objective To study the apo-E gene polymorphisms and the lipoprotein level character of different gene expression in patients with cerebrovascular infarction(CI) and intracerebral hemorrhage(ICH).Methord With case-control study method,the apo-E gene expression,its allele frequency and the levels of serum lipids in patients with cerebrovascular infarction or with intracerebral hemorrhage and the control were compared.Result The CI group had a higher apo-E ?4 allele frequency(10%) than controls(4.6%)(P