Objective: To observe clinical therapeutic effect of Naolisu Instant Granules for the patient of cerebral apoplexy at acute stage. Methods'. 90 cases were randomly divided into treatment group of 60 cases and control group of 30 cases. The treatment group was treated by oral administration of Naolisu Instant Granules and the control group was given Venoruton tablets, with oxygen inhalation, decreasing intracranial pressure, controlling blood pressure, preventing and treating infection, keeping water-electrolyte balance in the two groups. The changes of cumulative scores of TCM syndromes, cumulative scores of nerve function defect, and clinical therapeutic effects were compared between groups. Results: There were significant differences be- fore and after treatment in the changes of the cumulative score of TCM syndromes and the nervous function defect in the treatment group (P