Objective [WT5”BZ]To improve recognition and differential diagnosis of splenic space occupying disease.[WT5”HZ]Method [WT5”BZ]40 cases admitted from 1983 to 1999 were analyzed retrospectively。[WT5”HZ]Result [WT5”BZ]Twenty six out of 40 cases were of benign splenic disease including one case of cyst, 3 cases of splenic abscesses, 7 cases of splenic tuberculosis, 5 cases of splenic “true” cyst, 4 cases of splenic angiolymphoma, 3 cases of splenic aneurysm, and one each of splenic lymphoangioma, epidermoid cyst and hamartoma. There were 14 cases of malignant tumor, amongwhich,there were two cases of non Hodgkin′s lymphoma and two of leiosarcoma,one angiosarcoma and metastatic splenic malignant tumor in 9 cases.[WT5”HZ]Conclusion [WT5”BZ]Therapeutics should be adopted according the nature of splenic diseases, based on clinical and image characteristics.