74 cases of colorectal cancer patients who survived over ten years after radical operation were reported. It showed that the survival rate was significantly related to the location of tumor, Dukes' stage, metastasis of mesenteric lymph nodes and perioperative transfusion. It was emphasised that early diagnosis and treatment are important, and could increase the survival rate after operation. In patients who have local invasion or single metastasis, multiorgan resection should be performed if necessary. Adjunctive multi-treatment measures such as preoperative irradiation, arterial chemotherapy, preoperative chemotherapy per rectum, intra-peritoneal hyperthermic perfusion during operation, postoperative irradiation and chemotherapy may contribute to cure.