PURPOSE: Chronic pelvic pain syndrome(CPPS) is the most common category of the chronic prostatitis. CPPS is a poorly defined, multifactorial condition characterized by pelvic pain and voiding symptoms. The effectiveness of extracorporeal magnetic innervation(ExMI) therapy was evaluated in patients with CPPS. MATERIALS AND METHODS: From July 2003 to December 2004, 28 men who were diagnosed with CPPS who were refractory to medication underwent ExMI therapy for 2 visits weekly for 8 weeks. The patients completed the National Institute of Health Chronic Prostatitis Symptom Index(NIH-CPSI) and a maximal flow rate index. RESULTS: Significant decreases occured in NIH-CPSI pain(9.7 to 8.3, p <0.05), NIH-CPSI urination(4.4 to 3.9, p <0.05), NIH-CPSI quality of life 8.7 to 7.7, p <0.05), and total NIH-CPSI(22.8 to 19.9, p <0.05) scores after treatment. There was an insignificant decrease in the maximal flow rate(21.5 to 21.4, p> 0.05) score after treatment. CONCLUSIONS: ExMI therapy effectively improves the symptoms of CPPS. ExMI therapy appears to be a safe and effective treatment in improving both the symptoms and the quality of life of men with CPPS refractory to conventional treatment. A larger controlled study is required to confirm these results.