The Ewha Medical Journal  2014;37(2):105-108

doi:10.12771/emj.2014.37.2.105

Cytomegalovirus Colitis with Colon Perforation and Lower Gastrointestinal Bleeding in a Immunocompetent Patient.

Sun Wook KIM 1 ; Yoon Jin CHA ; Min Hwan KIM ; Moo Nyun JIN ; Jung Hee LEE ; Hye Jung PARK ; Sooyun CHANG ; Hyuk LEE

Affiliations

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Keywords

Cytomegalovirus; Colitis; Immunocompetence

Country

Republic of Korea

Language

Korean

Abstract

Cytomegalovirus (CMV) infection in immunocompromised patients is associated with significant morbidity, mortality, and adverse clinical outcome. However, CMV infection in immunocompetent patients has been considered to have subclinical and self-limited course, and does not require treatment. We reports a case of CMV colitis, presented with colon perforation and lower gastrointestinal bleeding in a immunocompetent 31-year-old young male. After conservative treatment, colonoscopy revealed multiple ulcers in transverse colon. CMV colitis was confirmed by microscopic findings and immunohistochemistry. After successful treatment with ganciclovir, the patient improved without invasive procedure.