Clinical and Experimental Otorhinolaryngology  2014;7(1):63-65

Aggravation of Relapsing Polychondritis due to the Infection and Its Manifestation on a Nasal Tip Graft.

Seung Beom SON 1 ; Woo Hee HAN ; Jae Hong PARK ; Hyun Pyo HONG ; Sung Won YOON ; Soo Chan JUNG ; Mi Ra KIM ; Young Jin KIM ; Hyun Seok LEE ; Soo Bin SON ; Woo Sung CHO

Affiliations

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Keywords

Relapsing polychondritis; Nose; Cartilage; Antibody; Foreign-body reaction

Country

Republic of Korea

Language

English

Abstract

Relapsing polychondritis (RP) is an uncommon systemic disease that is characterized by episodic and progressive inflammation of the cartilaginous structures, which can be very debilitating and in some instances life-threatening. The pathogenic pathways of RP are largely unknown. However, several hypothesis have been suggested. We had an interesting case of aggravation of RP due to the infection. Graft cartilage on the nasal tip was affected by RP also. This case can give a clue of revealing the pathogenesis of RP. We introduce a case with a review of the literature.