Chinese Journal of Forensic Medicine 2016;31(5):463-466

doi:10.13618/j.issn.1001-5728.2016.05.009

The application of mRNA in body lfuid identiifcation and tissue resource(

Hemiao ZHAO ; Chong WANG ; Wanshui LI ; Zheng TU ; Xiulan XU ; Hui SUN ; Lan HU

Keywords

forensic biological evidence; mRNA; body lfuid stains; tissue resource identiifcation

Country

China

Language

Chinese

Abstract

The identiifcation of body lfuid and their tissue resource is an important part of forensic medicine research. Conventional methods have imperfections like high false positive rate and may destroy biomaterial, which should be replaced by a new conifrmatory test. Highly-differentiated cells express speciifc mRNA molecules that can be used for body lfuid identiifcation. These mRNA markers can identify body lfuids like peripheral blood, menstrual blood, semen, saliva, vaginal secretion, skin-contact stains. This method have favorable sensitivity, speciifcity and can be detected after years, made it a ideal way to identify current body lfuids in the future. This review focus on the application of mRNA in body lfuid identiifcation and tissue resource.