Progress in Modern Biomedicine 2005;5(3):1-6

doi:10.3969/j.issn.1673-6273.2005.03.001

Effects of extremely low frequency magnetic field on growth kinetics, metabolism and cell cycle of human liver cancer cells

Liang DONG ; Lingzhen HUANG ; Yantian CHEN ; Tao GENG ; Dengming XIAO ; Hanshi QI

Keywords

ELF magnetic field; human liver cancer cell; proliferation activity; growth kinetics; metabolism; cell cycle

Country

China

Language

Chinese

Abstract

Objective: To study the effects of extremely low frequency (ELF) magnetic field with fixed parameters on human liver cancer cells (SK-HEP-1) at different aspects. Methods: SK-HEP-1 cells were exposed to 50Hz, 20mT magnetic field during the whole culture process, and then proliferation activity, growth kinetics, metabolic profile and cell cycle were analyzed. Results: 50Hz, 20mT magnetic field inhibits the growth and metabolism of SK-HEP-1 cells, and hampers their mitotic division. Conclusion: 50Hz, 20mT magnetic field could be a potential therapy in the treatment of human malignant tumors.