PURPOSE: This study was done to identify the degree of job stress for workers with mentally disabled and factors influencing their job stress. METHODS: The participants in this study were employees with mental disabilities employed in job programs sponsored by community mental health centers and social rehabilitation centers. For this study, researchers conducted a survey with structured questionnaires with 221 employees. Data were analyzed using t-tests, ANOVA, Pearson's correlation coefficients and multiple regression analysis with SPSS/WIN 14.0. RESULTS: There were no significant differences in job stress according to general characters. However, there were significant differences in job stress according to type of employment and monthly-income. Multi-regression analysis showed that type of employment and social support affected job stress. CONCLUSION: The findings of this study indicate that following should be emphasized: conditions of employment such as type of employment and social support should be improved to decrease job stress and help the employee to remain in the job.