Chinese Journal of Rehabilitation Theory and Practice 2016;22(4):399-403

doi:10.3969/j.issn.1006-9771.2016.04.006

Establishment of A Model in Rat Brain Nuclei Microelectrode Recording Coupled Behavioristics for Rehabilitation Experiment

Shenghao ZHANG ; Nan LI ; Shunnan GE ; Yang LI ; Songyan WU ; Xuelian WANG ; Chaohui LIU

Keywords

microprobe recording; self-administration; cerebral function; rehabilitation; neurophysiology

Country

China

Language

Chinese

Abstract

Objective To establish a coupled model combining the rat brain nuclei microelectrode recordings and the behavioristics for rehabilitation experiment. Methods The modified indwelling tube connection fixed device was put inside the rats' back, and the microprobes were implanted into related neural nucleus. A signal connection was made between self-administration system and electrophysiological data acquisition system. The rat was addicted after training by self-administration system. The related cerebral nucleus electrophysiological sig-nals were recorded in different states of addiction. Results and Conclusion The modified indwelling tube connection fixed device has a bet-ter quality for reducing the phenomenon of leak. The signal was well in the combination of two different systems. The signals for the rat's ac-tion and neural electrical were recorded in the same time.