Journal of International Pharmaceutical Research 2015;(4):413-426

doi:10.13220/j.cnki.jipr.2015.04.001

Techniques and strategies for characterization and isolation of chemical components of traditional Chinese medicines

Baiping MA ; Liping KANG ; Xu PANG ; Renyi YAN

Keywords

traditional Chinese medicine; chemical composition; LC-MS; characterization; supercritical fluid chromatography; MCI; isolation

Country

China

Language

Chinese

Abstract

The chemic al composition of traditional Chinese medicine (TCM) is the material base for its prevention and treatment of disease. Characterization, analysis and isolation of chemical constituents, important fields of modern research on TCM, however, are still a great challenge due to the complexity. In recent years, considerable progress has been made in these fields with the application of new chromatographic packing materials and methods, analysis technologies represented by LC-MS and the associated databases and softwares. Here, the advancement of methods and strategies used in the research on the chemical constituents of TCM is briefly reviewed.