Objective: To explore the effect of basis of periodontal therapy in patients with aggressive periodontitis of clinical therapeutic. Methods: Select 80 cases of aggressive periodontitis patients from January 2013 and January 2014,randomly divided into experimental group and control group, control group patients received routine treatment with antibiotics, liuwei dihuang pill and vitamin C, and the experimental group received treatment for periodontal basic treatment on the basis of routine treatment, after the treatment period, compared two groups of patients before and after treatment of cross periodontal probing depth (PD), explore clinical bleeding index (BOP), attachment level (AL) and two sets of teeth is loose. Results:After the treatment period, Periodontal probing depth of diagnosis (PD), explore clinical bleeding index (BOP), attachment level (AL) value is decreased obviously, and the improvement of the experimental group patients condition is more apparent, and at the end of the observation period, loose teeth number of patients is less than that of controls, statistical results have obvious difference (x2=12.17, x2=12.94;P<0.05). Conclusion:For aggressive periodontitis patients, periodontal basic treatment is a kind of curative effect and effective treatment, can help patients to improve the clinical symptoms as soon as possible, can be suitable for clinical promotion.