In 2007, Transatlantic Cooperation Society Consensus Ⅱ(TASCⅡ) Conference Guideline has divided the aortoiliac artery and femoral popliteal artery diseases into 4 types , suggesting that endovascular treatment should be employed for TASC-A type lesions, individualized therapy should be adopted for TASC-B and TASC-C type lesions when a variety of factors are taken into consideration , and surgical treatment should be used for TASC-D type lesions. In recent years, along with the development of imaging technique and material science as well as the improvement of interventional operator ’s skill, the mini-invasive interventional therapy has been more and more performed for the relatively complex TASC-D type aortoiliac artery and femoral popliteal artery occlusive diseases , and satisfactory clinical curative effect has been achieved. This paper aims to make a comprehensive review about the current situation of endovascular treatment for lower extremity arteriosclerosis obliterans of TASC-D type in clinical practice.