Chinese Journal of Information on Traditional Chinese Medicine 2015;(7):128-130

doi:10.3969/j.issn.1005-5304.2015.07.040

Research Progress in the Anti-tumor Mechanism of Action of Tanshinone IIA

Jie YANG ; Jie LI ; Shulong JIANG

Keywords

tanshinone ⅡA; anti-tumor; mechanism of action; review

Country

China

Language

Chinese

Abstract

Tanshinone ⅡA has a broad anti-tumor activity and good prospects for clinical application. Its possible mechanism of action involves the regulation of cell cycle, inhibition of cell proliferation, induction of apoptosis, inhibition of tumor invasion, metastasis and inhibition of angiogenesis, and reversal of multidrug resistance. This article reviewed the research progress of anti-tumor effect of tanshinone ⅡA in recent years.