Chinese Journal of Endocrinology and Metabolism 2015;(6):544-547

doi:10.3760/cma.j.issn.1000-6699.2015.06.018

Recent progress in studying type 2 diabetes mellitus and tumor risk

Yuehong CHEN ; Liang DU ; Chunlin ZHANG ; Xingyuan GENG ; Guanjian LIU

Keywords

Diabetes mellitus,type 2; Neoplasms; Drugs

Country

China

Language

Chinese

Abstract

[Summary] During recent years, increasing evidences have indicated that type 2 diabetes mellitus(T2DM) might increase the risk of certain tumors; the process might be not only related with the chronic pathologic status of T2DM such as hyperglycemia, hyperinsulinemia, insulin resistance, dyslipidemia, status of chronic inflammation but also associated with the long-term use of anti-diabetic drugs (i. e. sulfonylureas, biguanides, glitazones, dipeptidyl peptidase-4 inhibitors, glucagon-like peptitide-1 receptor agonists), as well as the use of insulin and insulin analogues. Herewith a system review was made about the recent progress in studying T2DM and tumor risk.