Chinese Journal of Endocrinology and Metabolism 2015;(6):552-554

doi:10.3760/cma.j.issn.1000-6699.2015.06.020

Effects of antidiabetic agents on bone metalbolism in diabetic patients

Xia LI ; Tao LEI

Keywords

Antidiabetic agents; Diabetes; Bone metabolism; Osteoporosis; Fracture

Country

China

Language

Chinese

Abstract

[Summary] The prevalence of diabetes mellitus and osteoporosis is rapidly growing and pose a serious threat to human health,. Accumulating evidence indicates that diabetes mellitus is a risk factor for osteoporosis and they could be linked by similar pathophysiological mechanisms. Antidiabetic agents may not only help to control the chronic hyperglycemia state but can also effect bone, This article reviewed the correlation between diabetes mellitus and bone metabolism and summarized the available data on skeletal effects of clinically approved antidiabetic therapies, aimed to provide the basis for clinical medicine use.