Chinese Journal of Comparative Medicine 2015;(6):71-74

doi:10.3969/j.issn.1671.7856.2015.006.014

Application of suckling mice in pediatric pharmacological and toxicological studies

Chengyu PIAO ; Min YU ; Yongwu LIU ; Shumin LIU

Keywords

Pediatric drugs; Suckling mice; Pharmacology; Children; Toxicology

Country

China

Language

Chinese

Abstract

Research on laboratory animals is an important issue in biomedicine.Children are a special drug-using population.The selection of suitable experimental animals is a key issue to ensure the scientific quality of research for pediatric drugs.Based on the review of a large number of literature, the authors summarized the application of suckling mice in the pharmacological research and toxicological evaluation of pediatric drugs for the treatment of common diseases in children.We also summarized the existing problems in pediatric toxicology and proposed solutions for providing a reference of test animal application in pediatric drug research.