Chinese Journal of Gastroenterology 2015;(5):311-313

doi:10.3969/j.issn.1008-7125.2015.05.013

Advances in Study on Mechanisms of Non-steroidal Anti-inflammatory Drugs-induced Small Intestinal Injury and the Preventive and Therapeutic Effect of Muscovite

Dan LLANG ; Hui DONG ; Liang ZHAO ; Lina MENG

Keywords

Anti-Inflammatory Agents,Non-Steroidal; Small Intestinal Injury; Muscovite; Therapy

Country

China

Language

Chinese

Abstract

Non-steroidal anti-inflammatory drugs( NSAIDs)are widely used in clinical practice,and their gastrointestinal adverse effects have attracted more and more attentions. Although many investigations were focused on gastroduodenal mucosal injury induced by NSAIDs over times,small intestinal injury has become the new hot-spot because of its high morbidity rate in recent years. The mechanisms of NSAIDs-induced small intestinal injury have not been fully elucidated and no specific prevention and treatment modalities have been developed. In this article,the mechanisms of NSAIDs-induced small intestinal injury and the preventive and therapeutic effect of muscovite were reviewed.