Chinese Journal of Applied Clinical Pediatrics 2014;29(9):653-654

doi:10.3760/cma.j.issn.2095-428X.2014.09.004

Do immunoglobulin A vasculitis and immunoglobulin A nephropathy belong to one desease

Xiaochuan WU ; Juan LIAO

Keywords

IgA vasculitis; IgA nephropathy; Abnormal glycosylation of IgA1 molecule; IgA deposition

Country

China

Language

Chinese

Abstract

The immunopathogenesis of IgA vasculitis and IgA nephropathy both demonstrate IgA deposition,and abnormal glycosylation of IgAl molecule is their major pathogenesis.Therefore,it is clinically controversial that they are actually one disease.The present text will delineate their similarities and differences from aspects of epidemiology,clinic,pathology,mechanism and prognosis.