Pediatric allergy,immunology and rheumatology (PAIR) discipline is one of the important branch of pediatrics in China.It covers the pediatric allergic diseases,immunodeficiency diseases,rheumatic diseases and the clinical and research aspect which is associated with infection and immunity including inflammation,and inflammatory diseases,et al.Though it is an interdisciplinary discipline which has a long history and being paid great attention and construction rapidly in early a decade,but it is still in the early stages of development in China.How to promote its reasonable,scientific,and further development quickly to adapt to the high-speed social medical service growth of demand in this field is an important task which we have to face to.This article reviews the discipline development history,present situation and futue trend.