Objective To realize the clinical and epidemiological characteristics of measles,and explore effective measures to control measles epidemic.Methods Clinical data of 554 hospitalized measles children between January 2009 and December 2013 were analyzed retrospectively.Results All children had fever,cough,and skin rash,507 (91.52% )had typical clinical manifestations of measles,47(8.48% )had mild manifestations;the major population were children aged≤6 months(n= 176,31.77% )and 7-8 months (n= 346,62.45% );132 (23.83% )children had contact history of confirmed measles,19(3.43% )measles children’s mothers also developed measles (all were cases of 2013),227 (40.97% )children had history of repeated infusion or hospitalization in large medical institutes dur-ing the measles incubation period (all were cases of 2013,there were measles children who had infusion or hospitali-zation in the same hospital during the same period). The peak incidence of measles usually occurs in January-May. Conclusion Intensive immunization of measles for young women of reproductive age and vaccination with“pre-mea-sles vaccine”for early infancy,and strengthening the medical management of fever outpatients are important meas-ures to prevent measles epidemic.