Chinese Journal of Gastroenterology 2014;(5):312-314
doi:10.3969/j.issn.1008-7125.2014.05.015
Expression and Role of Brain-derived Neurotrophic Factor in Intestinal Tract
Shujuan JING ; Shiwei YANG ; Zhi LI ; Junning LIU
Keywords
Brain-Derived Neurotrophic Factor; Intestinal Sensitivity; Intestinal Motility; Receptor Protein-Tyrosine Kinases
Country
China
Language
Chinese
Abstract
Brain-derived neurotrophic factor (BDNF)is both a neurotrophic substance and a neurotransmitter.BDNF and its receptors are highly expressed in enteric nervous system,intestinal mucosal epithelium and intestinal muscularis, which play an important role in regulating intestinal sensitivity and motility.This article reviewed the expression and role of BDNF in intestinal tract.
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