Chinese Journal of Gastroenterology 2014;(5):294-296

doi:10.3969/j.issn.1008-7125.2014.05.010

Advances in Studies on RKIP and MMP-9 in Colorectal Cancer

Lanming LOU ; Liping SHI ; Xiuwei SUN

Keywords

Raf Kinase Inhibitor Protein; Matrix Metalloproteinase-9; Colorectal Neoplasms; Signal Transduction

Country

China

Language

Chinese

Abstract

Raf kinase inhibitor protein (RKIP)is a member of the phosphatidylethanolamine-binding protein family, which can inhibit the metastasis of tumor cells and is closely associated with the occurrence and development of tumor. Matrix metalloproteinase-9 (MMP-9)is a endopeptidase that can degrade extracellular matrix and plays an important role in invasion and metastasis of tumor.This article reviewed the advances in studies on RKIP and MMP-9 in colorectal cancer.