Objective To understand the epidemic situation of common human soil-transmitted nematode infections in Quan-zhou City in 2012,so as to provide the evidence for improving the prevention and control measures. Methods The residents aged above 3 years from 5 townships in 2 counties were investigated to detect the parasite eggs(hookworm,Ascaris lumbricoides,Trich-uris trichura)by Kato-Katz technique. One kindergarten of each county was randomly selected and 228 children were investigated to detect Enterubius vermicularis eggs by the cellophane tape anus test. Results The total hookworm infection rate was 3.60%(69/1919). For the hookworm infection rates,there was no significant difference among different areas and between different genders, but there were significant differences among different age groups and different careers. No Enterubius vermicularis eggs were detect-ed. Conclusion The effect of the prevention and control of Ascaris lumbricoides,Trichuris trichura and Enterubius vermicularis in-fections is remarkable. However,the infection rate of hookworm has a rising trend and the prevention and control of hookworm in-fection should be strengthened.