Journal of Zhejiang Chinese Medical University 2014;(2):224-226
Review on Study of Anti-tumor of Raddeanin A
Gang XUE ; Xi ZOU ; Ruiping WANG
Keywords
Raddeanin A; cancer; anti-tumor activity; structure; cellapoptosis
Country
China
Language
Chinese
Abstract
[Objective]To review the antitumor progress of Raddeanin A in nearly 10 years. [Method] Col ecting the antitumor research literature about Raddeanin A for nearly 10 years, describing its antitumor research mechanism, such as inducting of cellapoptosis blocking the cellcycle, blocking STATs signaling pathways and inhibiting the tumor angiogenesis. [Result] Raddeanin A could induce the H460 cellapoptosis, block LoVo cellcycle and STATs signaling pathways of LoVo cells, and inhibit HepG-2 cellangiogenesis. [Conclusion] The antitumor mechanism of Raddeanin A could be inducting of cellapoptosis, blocking the cellcycle, blocking STATs signaling pathways and inhibiting the tumor angiogenesis.
备案号: 11010502037788, 京ICP备10218182号-8)