Chinese Journal of Endocrinology and Metabolism 2013;29(9):772-773

doi:10.3760/cma.j.issn.1000-6699.2013.09.009

Study on CXCL5 gene polymorphisms in obese patients with type 2 diabetes mellitus

Yanru ZHAO ; Ximing QI ; Fuzai YIN ; Bo LIU ; Yu ZHOU ; Wen LIU

Keywords

Diabetes mellitus,type 2; CXCL5; Polymorphisms,gene; Obesity

Country

China

Language

Chinese

Abstract

The association between CXCL5 gene polymorphism and obese patients with type 2 diabetes mellitus (T2DM) was explored.The distribution of CXCL5 gene promoter region-156G/C polymorphism revealed no significant difference between normal control group and T2DM group (P＞0.05).The frequency of C allele gene in obesity group was higher than that in non-obesity group(P＜0.05).The results suggest that the CXCL5 promoter gene -156G/C polymorphsim has no relation with T2DM,but it is a risk factor for obesity.