Chinese Journal of Internal Medicine 2013;52(10):833-837
doi:10.3760/cma.j.issn.0578-1426.2013.10.009
A standardization study of Meta-analyses on nephropathy published in Chinese journals
Jinyan LIU ; Yuliang ZHAO ; Qinghua ZHOU ; Yumei WU ; Shengguo ZHOU ; Ling ZHANG ; Ping FU
Keywords
Meta-analysis; Nephrology; Chinese journals; QUOROM Statement; MOOSE Checklist
Country
China
Language
Chinese
Abstract
Objective To evaluate the standardization of Meta-analyses on nephropathy published in Chinese journals.Methods By searching in WANFANG,VIP,CNKI databases and Chinese Biomedical Literature Database(CBM) as well as related Chinese journals,eligible Meta-analyses were enrolled and analyzed according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) Statement and the MOOSE (Meta-analysis of Observational Studies in Epidemiology) Checklist.Results A total of 217 Meta-analyses were enrolled with 166 on randomized controlled trials (RCT) and 51 on observational studies.Based on the PRSIMA Statement,of the 166 Meta-analyses on RCT,51.8%(86 papers) were found with the complete research hypothesis,13.9% (23) with the literature screening flow chart,15.7% (26) with the subgroup analysis,53.0% (88) with the publication bias analysis and 28.3% (47) with the sensitivity analysis.According to the MOOSE Checklist,of the 51 Meta-analyses on observational studies,only 9.8% (5) had done the statistical stability calculation,54.9% (28) with the outlook of application,45.1% (23) with the limitation of the study,2.0% (1) with the quantitative analysis on potential bias and 17.6% (9) with the suggestion for future studies.Conclusions Unclear hypothesis,limited methodological description,lack of in-depth analysis on heterogeneity and bias are the common defects in Meta-analyses published in Chinese journals on nephrology.
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