Cancer Research and Clinic 2013;25(9):646-648

doi:10.3760/cma.j.issn.1006-9801.2013.09.025

Research progress of new anticancer drug lobaplatin in treatment of metastatic breast cancer

Xu SUN ; Donghu SUI

Keywords

Lobaplatin; Metastatic breast cancer; Pharmacodynamics; Clinical research

Country

China

Language

Chinese

Abstract

As the third generation platinum antitumor drug with independent intellectual property rights,a number of basic and clinical research shows lobaplatin can effectively inhibit the proliferation of human breast cancer cell lines including triple-negative breast cancer in vivo.Compared with the cisplatinbased regimens,lobaplatin-based regimens have similar efficacy,and better safety profile.It becomes the new treatment option of metastatic breast cancer,and remains to be further study to optimize clinical rational drug use.