Objective: To explore how to further improve the drug administration in maternal and child health care hospital at county level. Methods: Based on the internal requirement and significance of drug administration in maternal and child health care hospital at county level. We analyzed the essence of drug administration, importance of strengthening drug administration in maternal and child health care hospital at county level under circumstance of health care reform and existing difficulty in the drug administration at present time. In the end, we developed our own points of view on how to improve drug administration in maternal and child health care hospital at county level. Results:Maternal and child health care hospital at county level should adapt the new challenge under circumstance of health care reform, improve the management. Conclusion:According to the new health care reform, it is vital to enhance self performance steadily and consistently as to achieve the improvement of drug administration and service quality gradually.